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Multi-site TMS
Multisite TMS uses the use of multiple stimulation coils that are independently controlled.
Each coil can be controlled with individual settings for time, frequency, strength and spacing.
Therefore, the operator can stimulate multiple locations with or without a time delay between stimulation pulses.
Multisite TMS can also be used to suppress one stimulus side and activate the other.
The main building blocks for the coils used in multi-channel TMS are the use of distributed coils due to the need for closer size and focus.
Combined with MAG & More's 3D-Neuronavigation, you have complete and precise control of the stimulation target for all coils.
Combined with the TMS Coil Interface, you can independently control up to four PowerMAG systems simultaneously.
Therefore, up to four areas of the brain are stimulated within the network.
The corresponding USB device driver provides an open API that can be used to design complex stimulus programs.
Multi-site TMS equipment configuration
Double coil
PMD25-decentral
The small dispersion coil allows up to 4 stimulation sites to be used simultaneously.
PC INTERFACE ×4
Up to 4 stimulators can be controlled with 4 PC interfaces
Double coil
PMD25-decentral
Analog signal enables fast and accurate petameter setting
Multi-focal/multi-site TMS TMS survey is used to investigate functional connectivity in complex interconnected networks. By varying the timing and position of each coil, you can investigate temporal and spatial relationships between brain regions.
Another approach is to apply r-TMS to one or more brain areas and investigate using a single pulse stimulus to other areas. With a well-focused coil, up to four selected brain regions can be stimulated simultaneously with different patterns and intensities.
Key technical considerations
Safe and flexible operation of up to 4 PoweMAG devices
It must be possible to control multiple stimulators and coils via a single control instance (usually some form of computer).
Timing must be accurate and the output pattern must be stable for all stimulation patterns (single pulse, r-TMS, train, theta burst, ppTMS, QPS).
Coil size and capacity
Stimulating two spatially close brain regions simultaneously The application-oriented coil geometry is important for enabling multifocal stimulation. It can also be used at close range.
To stimulate areas of the brain that are very close to each other (eg, motor and premotor areas), the coils must be designed in a distributed fashion.
The PowerMAG multifocal system solution is not limited to interhemispheric stimulation.
An optional PowerMAG View! 3D Nueronavugation System is available for tracking all four coils simultaneously.
With a very high focal mini-coil, the PMD25-distributed type can stimulate two independent stimulation points at a distance of only 3-4 cm.